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phenobarbital will minimize the extent or impact of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Potent or reasonable CYP3A4 inducers could increase rate of diazepam elimination; consequently, efficacy of diazepam may very well be lowered.Phenobarbital is usually a barbituric acid spinoff for oral a